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Leptosperin is a naturally occurring chemical, found only in the nectar of Manuka plants (and a few very close relatives). It was first identified (and patented) by Japanese researcher Kato in 2014*.

*Kato Y, Fujinaka R, Ishisaka A, Nitta Y, Kitamoto N, Takimoto Y. Plausible authentication of Manuka honey and related products by measuring leptosperin with methyl syringate. J. Agric. Food Chem., 2014, 62 (27), pp 6400-6407

Leptosperin concentration is stable over time, and therefore measuring its concentration in honey is a good way of identifying whether the honey comes from Manuka nectar, and whether it can be labelled as Manuka, or a Manuka blend, or as a multi-floral honey. Leptosperin is the first of what could be a number of Manuka specific chemical markers, which are used to identify Manuka honey for authenticity and labelling purposes.

This patent is now licensed to the Unique Manuka Factor Honey Association (**UMF® Honey Association) and Fera is the only laboratory in UK to be the preferred partner by the UMF® Honey Association as an official testing laboratory for independently verifying the UMF® rating of Manuka honey

Fera offers chemical and microbiological analysis - including the new Leptosperin Manuka specific marker test to confirm the authenticity of honey labelled as 'Manuka'. All analyses are fully validated and performed to current industry standards.

Our New Leptosperin Test

A sub sample of honey is extracted in ultra-pure water, diluted and analysed by Ultra Performance Liquid Chromatography (UPLC). Fera is the only laboratory in UK to be the preferred partner by the UMF® Honey Association as an official testing laboratory for independently verifying the UMF® rating of Manuka honey




Leptosperin UPLC-UV-FLD 10 working days

Key Capabilities

  • We have extensive scope of UKAS (ISO17025) accredited tests with the ability to obtain the necessary UKAS accreditation with our 'flexible scope' approach
  • Specialists in unusual matrices, method development and validation
  • Technical advice and support pre and post analysis
  • Fera is the National Reference Laboratory in 7 different areas
Consultancy - if you have questions about honey product development, market acceptance, the regulatory environment, sometimes it requires another experienced person or team to help pull things together and move them ahead. Fera's consultancy service is made up of senior scientists who have broad and deep experience in the honey industry that we can bring to bear on your research project which goes beyond analysis and scientific expertise.

Contact Us

To speak with us about this services, or for any other services, please contact the Customer Service Group on +44 (0)300 100 0323 or e-mail us at

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How to take and submit a sample

To have your honey tested you need to send approx. 50g of honey in a plastic container with a screw lid. The sample should not contain wax and just be a representative sample. Download and complete our Food Generic Sample submission form and send it along with your samples to;

Ella Patel (Food Analysis)

Fera Science Ltd

Sand Hutton

York, YO24 4EJ

Download our Sample submission form here: Food Generic Sample Submission Form

Contact Us - Food

T: +44 (0)300 100 0323

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Download the latest brochure here Food Integrity & Traceability brochure

  • Extensive scope of UKAS (ISO17025) accredited tests
  • National Reference Laboratory Status
  • Extensive range of experts & multiplex testing where possible

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National Reference Laboratory

We are the National Reference Laboratory for:

  • Food, Feed and Food Contact Materials
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