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NIAS - Non-Intentionally Added Substances

Non-Intentionally Added Substances (NIAS) are chemical compounds that are present in food contact material but have not been added for a technical reason during the production process.

food contact testing, surveillance, targeted and non targeted analysis, known migrants, unknown migrants

Fera is the UK National Reference Laboratory for Materials and Articles in Contact with Food. Our staff are experts in policy and legislation in this area as well as in analysis of migrating substances from these materials or articles. We develop and validate methods using advanced analytical technologies for a variety of FCM related substances. Our expertise in this area focuses on research, surveillance and targeted and non-targeted analysis of known and unknown migrants in food contact materials and articles, foods and food simulants, providing solutions for the challenges faced in the complex food supply chain that exists.

Our Services - Targeted & Non-Targeted Analysis

What are IAS? (Intentionally Added Substances)

IAS are known ingredients from food contact materials which can migrate such as monomers, catalysts, solvents, suspension media, additives, etc. Fera can test the migration of IAS into food simulants and foodstuffs to confirm compliance with Regulatory migration limits.

What are NIAS? (Non-Intentionally Added Substances)

NIAS are known or unknown isomers, impurities, reaction products and breakdown product of these ingredients as well as possible contaminants from the manufacturing process such as recycled materials, irradiated materials or contamination from indirect food contact sources such as printing inks, external coatings, adhesives, secondary packaging. Fera has extensive experience in the detection and measurement of NIAS in a range of material types and their migration into food simulants and foodstuffs. Close working relationships between FCM manufacturers and Analytical Laboratory allows an iterative process during new product development ensuring better understanding of components of ingredients, ideally leading to more 'predictable' NIAS.

food contact testing, surveillance, targeted and non targeted analysis, known migrants, unknown migrants

Dr Malcolm Driffield will be also speaking at the ILSI Europe International Symposia on Food Packaging which is held every four years and is internationally recognised as a scientific forum to discuss the science that ensures the safety and quality of food packaging. Following the success of the 5thsup> Symposium on Food Packaging: Scientific Developments supporting Safety and Innovation held in Berlin in November 2012, this 6th symposium will be emphasising again the innovations in the area of food packaging.

This event gathers together leading experts on a vast array of specialisms within the context of food contact materials (FCM) in foodstuffs.

Dr Malcolm Driffield is a real expert in his field of NIAS (Non-Intentionally Added Substances)/IAS (Intentionally Added Substances) in food contact materials in foodstuffs will be speaking.

His report will focus on 'Approaches for the determination of non-intentionally added substances (NIAS) as part of safety by design: Detection, quantification and risk assessment' which will include all the latest challenges facing the industry and where future trends are heading.


Learn More

Ever advancing analytical instrumentation provides very powerful tools for determination of IAS and NIAS so to speak with us about our services, or for any services not listed, please contact our recognised expert Dr Malcolm Driffield on:

+44 (0)300 100 0323 or contact us here.


Talk to an expert

Dr Malcolm Driffield is a recognised expert on the advanced analytical approaches for the determination of IAS and NIAS from food contact materials. At Fera we

  • Use state-of-the-art analytical techniques for targeted (IAS) and non-targeted (NIAS) analysis
  • Carry out profiling experiments to identify differences and similarities between sample sets
  • Work closely with customers to determine the most appropriate method for identifying and quantifying NIAS in specific cases

Explaining the science behind Food Contact Materials: Download our latest presentation by Dr Malcolm Driffield, recently launched at the Fresenius Conference

Telephone: +44 (0)300 100 0323

Email:      Contact Us

Download our latest white paper on NIAS

Our teams often work in other commercial industry partners to bring new ideas and innovation to the forefront and our latest white paper considers the 'Safety Assessment of Food Contact Materials' and describes the issues of chemicals migrating into food from packaging materials, the need to assess the safety of those chemicals that migrate, and the role that high-resolution mass spectrometry has to play in the related analysis.

To download the white paper click here

NRL for Materials & Articles in Contact with Food

We are the National Reference Laboratory for Materials & Articles in Contact with Food

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