Aquatic toxicology tests (assays) are toxicity tests used to provide qualitative and quantitative data on adverse effects on aquatic organisms from a toxicant. Toxicity tests can be used to assess the potential for damage to an aquatic environment and provide a database that can be used to assess the risk associated within a situation for a specific toxicant. Aquatic toxicology tests can be performed in the field or in the laboratory. Field experiments generally refer to multiple species exposure and laboratory experiments generally refer to single species exposure.
There are different types of toxicity tests that can be performed on various test species.
Different species differ in their susceptibility to chemicals, most likely due to differences in accessibility, metabolic rate, excretion rate, genetic factors, dieteary factors, age, sex, health and stress level of the organism. Common standard test species are;
the fathead minnow (Pimephales promelas), daphnids (Daphnia magna, D. pulex, D. pulicaria, Ceriodaphnia dubia), midge (Chironomus tentans, C. riparius), rainbow trout (Oncorhynchus mykiss), sheepshead minnow (Cyprinodon variegatu), mysids (Mysidopsis), oyster (Crassotreas), scud (Hyalalla Azteca), grass shrimp (Palaemonetes pugio) and mussels (Mytilus).
Tier 1 Studies with full GLP Compliance
Freshwater Alga and Cyanobacteria, Growth Inhibition Test
OECD 221 & OECD 239/239
Aquatic Plant Growth Inhibition Tests using Lemna sp. (OECD 221), Myriophyllum spicatum (OECD 238/239)
OECD 202 & OECD 211
Invertebrate testing using Daphnia magna, acute(OECD 202) and reproduction (OECD 211) including male induction (where necessary)
OECD 218/219, OECD 235 & OECD 233
Invertebrate testing using Chironomus riparius (OECD 218/219), also
acute (OECD 235) and full life cycle tests (OECD 233)
OECD 203, OECD 210 & OECD 305
Fish testing with a range of species as listed in OECD guidelines, including acute (OECD 203), Early life stage (OECD 210) and Bioaccumulation (OECD 305)
Our tests can be designed to meet EPA guidelines instead of, or as well as, the OECD guidelines as stated above, just get in touch on +44 (0)300 100 0324 or contact us here
Tier 2 Studies - Bespoke Capabilities
- We can develop tests that address particular concerns or information gaps using additional aquatic plant, invertebrate or fish species to support the development of Species Sensitivity Distributions (SDD) or the Geomean approach
- We are also able to refined Tier 1 tests, adapted to resemble pulsed exposures reflecting realistic to worst case scenarios
- We have expertise in testing to assess the potential for endocrine disruption in fish, e.g. biomarkers and/ or reproduction tests (OECD 229/230) and the sexual development test (OECD 234), should this be a consideration in your Environmental Risk Assessment
Our laboratories are equipped with state-of-the-art facilities that enable cost-effective performance of GLP compliant contract research environmental fate studies for pesticides, veterinary medicines, pharmaceuticals and industrial chemicals to satisfy regulatory requirements including:
- Laboratory (GLP) analytical services for agrochemicals, REACH, veterinary medicinal products
- Laboratory studies with radio-labelled and non-radiolabelled chemicals
- Batch sorption including aged sorption and column leaching studies according to OECD guidelines and parameter estimation
- Soil, water-sediment and manure/slurry biodegradation studies including estimation of degradation parameters and endpoints
- Hard (man-made) surfaces fate studies including lab-scale sorption, wash-off, and field monitoring studies
- Design, interpretation and analysis of lysimeter, field leaching, field dissipation and environmental (e.g. groundwater) monitoring studies
To speak with us about any of our aquatic ecotoxicology services, please contact our team on:
+44 (0)300 100 0324 or contact us here.
Contact Us - Aquatic Ecotoxicology
T: +44 (0)300 100 0324
Join Us at SETAC EUROPE BRUSSELS 2017
The SETAC Europe 27th Annual Meeting is dedicated to the use of multidisciplinary approaches to examine the impacts of stressors, chemicals, and technology on the environment. Also, to support the development of principles and practices for protection, enhancement and management of sustainable environmental quality and ecosystem integrity. Join us at 27th Annual SETAC EUROPE BRUSSELS 2017
Our Aquatic Ecotoxicology Capabilities
Fera can support our partners with an increasing testing capability in aquatic ecotoxicology for environmental risk assessments. All of our Aquatic Toxicology Testing is available with full GLP compliance.
Download our Latest Aquatic Ecotoxicology Leaflet
Come & Join Us at Chemicals Industries Regulations (CIR)
The CIR is dedicated to the advances in science and regulatory strategies to develop new biological and agrochemical products to meet the challenge of food security. Also, to support the development of principles and practices for protection, enhancement and management of sustainable environmental quality and ecosystem integrity. Join us at Chemicals Regulations Industry (CIR), 6-7 September 2017, Nice, France
Visit LIAISON website - Pesticide Approvals, Label Information & MRLs
Pesticide Approvals, Label Information and Maximum Residue Levels - LIAISON provides details of products approved for use on any crop you select
Case Study - Low Solubility (Water Sediment Study)
Fera can support our partners with the legal nature of the REACH authorisation process. Our latest case study illustrates a robust tailored study design that not only incorporated regulatory requirements, but also ensured the analytical challenges posed by the plasticizer were considered.
Download our Case Study on Low Solubility
Contact Us - Aquatic Ecotoxicology
T: +44 (0)300 100 0324
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